When Your Gut Isn’t Absorbing

Joseph Lopez • December 20, 2025

The Case for IV Micronutrients in Malabsorption, Autoimmunity & POTS

For many people, taking supplements feels like doing the “right thing.” But what if your body isn’t actually absorbing them?


This is a growing issue — especially among individuals dealing with:


  • chronic gut inflammation
  • autoimmune conditions
  • dysautonomia and POTS
  • long-term stress
  • infections
  • food sensitivities
  • medication-related gut damage


In these cases, oral vitamins and minerals may never make it past the digestive tract in meaningful amounts.


That’s where IV micronutrient therapy becomes not just helpful — but essential.

The Gut-Absorption Problem No One Talks About


Healthy digestion is required for nutrient absorption. Unfortunately, many modern conditions disrupt this process, including:


  • leaky gut
  • IBS and IBD
  • celiac disease
  • chronic infections
  • autoimmune disorders
  • proton pump inhibitors (PPIs)
  • antibiotics
  • chronic stress and cortisol dysregulation


When absorption is impaired, even high-quality supplements can pass through the body unused.


Symptoms often persist despite “doing everything right.”

Why IV Therapy Works When Oral Supplements Fail

IV therapy bypasses the gastrointestinal system entirely, delivering nutrients directly into the bloodstream.


This allows for:


100% bioavailability

No digestive breakdown or absorption variability.


Immediate cellular uptake

Nutrients reach tissues within minutes.


Higher therapeutic doses

Some deficiencies require concentrations that oral supplements can’t provide.


Consistent results

Especially important for chronic conditions.

IV Therapy and POTS: A Unique Advantage

Postural Orthostatic Tachycardia Syndrome (POTS) is often associated with:


  • chronic dehydration
  • electrolyte imbalances
  • autonomic nervous system dysfunction
  • low blood volume
  • mitochondrial dysfunction


IV fluids and micronutrients can help by:


  • expanding plasma volume
  • restoring sodium, magnesium, and potassium levels
  • improving circulation
  • supporting mitochondrial energy
  • reducing fatigue and brain fog


Many POTS patients report noticeable improvement in symptoms such as dizziness, palpitations, and exercise intolerance following IV therapy.

Autoimmunity, Inflammation & Nutrient Depletion

Autoimmune conditions create a perfect storm for nutrient depletion:


  • chronic inflammation increases nutrient demand
  • immune activation consumes antioxidants
  • medications interfere with absorption
  • oxidative stress damages mitochondria


IV nutrients help calm inflammatory pathways and support immune regulation.


Key IV nutrients for autoimmune support often include:


  • Vitamin C
  • Glutathione
  • Magnesium
  • B-Complex Vitamins
  • Zinc
  • Trace minerals


Together, they support detoxification, immune balance, and cellular resilience.

Signs You May Have Absorption Issues

  • Taking supplements with little benefit
  • Chronic fatigue or weakness
  • Brain fog
  • Lightheadedness or dizziness
  • Digestive discomfort
  • Frequent infections
  • Poor recovery from exercise
  • Nutrient deficiencies on lab work
  • These are often clues that oral supplementation alone isn’t enough.

How Often Should IV Therapy Be Used in These Conditions?

Protocols vary, but many patients benefit from:


  • Weekly infusions initially
  • Biweekly or monthly maintenance


Consistency is key when absorption issues are chronic.

The Bottom Line

If your gut isn’t absorbing nutrients properly, your cells are operating at a deficit — no matter how healthy your diet or supplement stack looks on paper.


IV micronutrient therapy offers a direct, efficient way to restore hydration, nutrients, mitochondrial function, and energy when oral intake isn’t enough.


For those dealing with malabsorption, autoimmunity, or POTS, IV therapy can be a powerful part of a comprehensive wellness strategy.

Support Your Body When Digestion Falls Short

Mike’s Vitamin Infusions provides personalized IV therapy protocols designed to bypass gut absorption issues and deliver nutrients directly to your cells.


Schedule your infusion today and give your body the support it needs — without relying on digestion to do all the work.

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