Beyond the Drip: How IV NAD⁺ Therapy May Boost Cellular Longevity
Beyond the Drip: How IV NAD⁺ Therapy May Boost Cellular Longevity
If you’ve spent any time exploring the world of longevity, you’ve probably come across one molecule that everyone’s talking about: NAD⁺ (nicotinamide adenine dinucleotide). It’s the molecule associated with mitochondrial health, energy production, DNA repair, and many of the cellular pathways tied to aging.
But here’s the part most people don’t know:
Your NAD⁺ levels drop by up to 50% by middle age.
And by the time you’re 70? They’ve tanked dramatically.
This decline is linked to decreased energy, slower recovery, inflammation, and accelerated aging at the cellular level. That’s why NAD⁺ infusions have become one of the most sought-after IV therapies in the longevity space.
Let’s break down how it works — and why IV delivery may offer advantages over oral precursors.
What Is NAD⁺ and Why Does It Matter for Longevity?
NAD⁺ is essential for hundreds of biological processes, including:
- Producing ATP (your cells’ energy currency)
- Repairing damaged DNA
- Supporting mitochondrial function
- Activating sirtuins (nicknamed “the longevity proteins”)
- Regulating inflammation and oxidative stress
When NAD⁺ levels decline, everything from metabolic efficiency to cognitive performance can take a hit. You feel it even if you don’t realize it — in slower recovery, lower motivation, poor sleep, or mental fog.
Why NAD⁺ Declines With Age
Aging accelerates several NAD-draining processes:
- Chronic inflammation
- Oxidative stress
- DNA damage
- Increased activity of CD38 (an enzyme that consumes NAD⁺)
- Environmental toxins
- Poor sleep, Alcohol, Stress
This means your cells are burning through NAD⁺ faster than you can make it.
At some point, oral supplementation with niacin, NMN, or NR may not provide the rapid boost your cells need — especially if absorption is impaired.
Why IV NAD⁺ Therapy May Work Better Than Oral Supplements
IV administration bypasses the digestive tract and delivers NAD⁺ directly into the bloodstream. This allows for:
- Higher bioavailability-Oral NAD precursors rely on multiple metabolic steps and can be inconsistent.
- Immediate cellular uptake-Cells can access NAD⁺ directly instead of converting precursors.
- Faster effects-Many people report noticeable boosts in energy, cognition, and mental clarity within hours or days.
- Higher therapeutic dosing-IV infusions deliver levels that aren’t feasible with oral supplements.
How Mike’s Infusions Ensures IV Therapy Is Safe
1. Improved mitochondrial function- NAD⁺ is essential for mitochondrial ATP production. More NAD⁺ = more cellular energy.
2. Increased mental clarity and focus- Many clients describe a “mental upgrade” following an infusion.
3. Support for healthy aging and cellular repair- NAD⁺ activates sirtuins, which help regulate longevity pathways and DNA repair.
4. Enhanced metabolism- Better mitochondrial function can support fat oxidation and metabolic flexibility.
5. May help with recovery from stress, fatigue, or overtraining- NAD⁺ is heavily used during physical and emotional stress.
How Often Should You Do NAD⁺ IV Therapy?

Longevity-focused clients often schedule NAD⁺ infusions:
- Once weekly for 4–6 weeks (loading phase)
- Monthly for maintenance
But the ideal cadence depends on your goals, your physiology, and your response to the therapy.
Who Benefits Most From NAD⁺ Therapy?
- High-performance professionals
- Athletes or hard-training individuals
- Individuals seeking longevity optimization
- People with chronic fatigue or oxidative stress
- Those recovering from illness or metabolic dysfunction
If you’re already dialed in with diet, exercise, sleep, and supplements — NAD⁺ can be the missing link that ties your longevity strategy together.
The Bottom Line
NAD⁺ isn’t a trend — it’s a foundational molecule tied directly to how your cells produce energy, repair themselves, and age. IV delivery offers a targeted way to quickly replenish depleted levels and support long-term vitality.
If you're focused on longevity, optimizing hormonal health, and maximizing your healthspan, NAD⁺ infusions can be a powerful addition to your protocol.
Ready to Experience the Benefits of IV NAD⁺ Therapy?
If you're curious about how NAD⁺ can elevate your energy, mental clarity, and longevity, schedule your infusion today with Mike’s Vitamin Infusions — where precision IV therapy meets personalized wellness.




